publications

= equal contribution, c corresponding authors, collaborator profiles , see Google Scholar for an up-to-date and complete list

2025

  1. PNAS
    2025_snead/paraspeckles_gif.gif
    Immiscible Proteins Compete for RNA Binding to Order Condensate Layers
    Wilton T. Sneadc, Mary K. Skillicorn, Krishna Shrinivasc, and Amy S. Gladfelterc
    Media+News PDF Supp Code Website

2024

  1. bioRxiv
    2025_krueger/idps.gif
    Generalized Design of Sequence-Ensemble-Function Relationships for Intrinsically Disordered Proteins
    Ryan Krueger, Michael P Brennerc, and Krishna Shrinivasc
    PDF Supp Code Website
  2. DNA30
    Learning and Inference in a Lattice Model of Multicomponent Condensates
    Cameron Chalk, Salvador Buse, Krishna Shrinivas, Arvind Murugan, and Erik Winfree
    DOI PDF Website

2023

  1. Nat. Comm
    A model for organization and regulation of nuclear condensates by gene activity
    Halima H. Schede=, Pradeep Natarajan=, Arup K. Chakraborty, and Krishna Shrinivasc
    PDF Supp Code Website
  2. Biophys. J
    A model for cis-regulation of transcriptional condensates and gene expression by proximal lncRNAs
    Pradeep Natarajan, Krishna Shrinivas, and Arup K Chakraborty
    PDF Code Website
  3. Nat. Imm
    The phosphatidylinositol-transfer protein Nir3 promotes PI (4, 5) P2 replenishment in response to TCR signaling during T cell development and survival
    Wen Lu, Ynes A Helou, Krishna Shrinivas, Jen Liou, Byron B Au-Yeung, and Arthur Weiss
    PDF Website

2022

  1. bioRxiv
    Multiphase coexistence capacity in complex fluids
    Krishna Shrinivasc, and Michael P Brenner
    PDF Website

2021

  1. PNAS
    Phase separation in fluids with many interacting components
    Krishna Shrinivasc, and Michael P Brenner
    PDF Supp Code Website
  2. Cell
    RNA-Mediated Feedback Control of Transcriptional Condensates
    Jonathan E. Henninger=, Ozgur Oksuz=, Krishna Shrinivas=, Ido Sagi, Gary LeRoy, Ming M. Zheng, and 9 more authors
    Media+News PDF Code Website

2020

  1. Science
    Partitioning of cancer therapeutics in nuclear condensates
    Isaac A Klein, Ann Boija, Lena K Afeyan, Susana Wilson Hawken, Mengyang Fan, Alessandra Dall’Agnese, and 5 more authors
    PDF Supp Website

2019

  1. Mol. Cell
    2019_shrinivas/enhancer.png
    Enhancer features that drive formation of transcriptional condensates
    Krishna Shrinivas=, Benjamin R Sabari=, Eliot L Coffey, Isaac A Klein, Ann Boija, Alicia V Zamudio, and 5 more authors
    Media+News PDF Supp Code Website
  2. Nature
    Pol II phosphorylation regulates a switch between transcriptional and splicing condensates
    Yang Eric Guo, John C Manteiga, Jonathan E Henninger, Benjamin R Sabari, Alessandra Dall’Agnese, Nancy M Hannett, and 5 more authors
    PDF Website

2018

  1. PNAS
    Evolution of weak cooperative interactions for biological specificity
    Ang Gao=, Krishna Shrinivas=, Paul Lepeudry, Hiroshi I Suzuki, Phillip A Sharp, and Arup K Chakraborty
    Media+News PDF Supp Code Website
  2. Cell
    Transcription factors activate genes through the phase-separation capacity of their activation domains
    Ann Boija, Isaac A Klein, Benjamin R Sabari, Alessandra Dall’Agnese, Eliot L Coffey, Alicia V Zamudio, and 5 more authors
    PDF Code Website
  3. Science
    Coactivator condensation at super-enhancers links phase separation and gene control
    Benjamin R Sabari, Alessandra Dall’Agnese, Ann Boija, Isaac A Klein, Eliot L Coffey, Krishna Shrinivas, and 5 more authors
    Media+News PDF Supp Code Website

2017

  1. Cell
    A phase separation model for transcriptional control
    Denes Hnisz=, Krishna Shrinivas=, Richard A Young, Arup K Chakraborty, and Phillip A Sharp
    PDF Supp Code Website