Physics-centered machine learning for design of biomolecules and condensates

2026

1. biorXiv

   

   Physics-guided design of intrinsically disordered proteins.

   Neha Tyagi⁼, Jackson Boodry⁼, Vita Chou, Wilton T Snead, and Krishna Shrinivas^c

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2. PNAS

   

   Information processing driven by multicomponent surface condensates

   Aidan Zentner, Ethan V Halingstad, Cameron Chalk, Michael P Brenner, Arvind Murugan, Erik Winfree, and Krishna Shrinivas^c

   Media+News PDF Supp Code Website

   Our work was selected as the cover for the July 7 2026 weekly issue of PNAS!

2025

1. Nat. Com. Sci

   

   Generalized design of sequence-ensemble-function relationships for intrinsically disordered proteins

   Ryan Krueger, Michael P Brenner^c, and Krishna Shrinivas^c

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   This work was covered by Northwestern University and Harvard University.
   Our work was selected as the cover for the May 2026 issue of Nature Computational Science!